Growing up during World War 2 and Korea, for Sydney Bannon it was a time of exciting possibilities.
As the day of her wedding approaches, Sydney learns she has a life-threatening disease. In a panic, she cancels her wedding plans and goes into a deep depression.
Finally coming out of it she decides to Europe and, "see Naples and die."
On her European odyssey, she meets a survivor of Hiroshima and a Partisan that fought the Nazis. Then by a twist of fate, she meets three strangers who tell her about a Hungarian doctor that has had success in treating her condition. At first, she declines until one of the strangers tells her it might be her Last Chance.