Duty Call is about an ambitious, girl shy, boy named Tommy. He is one of the best video gamers in his school. He pairs up with a non-conforming, outspoken girl named Sarah, who is also an excellent gamer, to try and beat the newest action game. But when they reach the highest level, Tommy goes missing. After the FBI gets involved, they realize that it's more then just a game. Real people are dieing on the other end of the controller. After Sarah tries to help the FBI find Tommy by playing the game with the help of his friends, she goes missing also. When the two of them are forced to kill the President of the United States by their captives using their gaming skills, they manage to use the game against those who created it.