Spanning the mid-1970s to the early 1990s, "Midge's Irish" delves into the life of Warren Le Blanc, a state hospital patient who resisted institutionalization for years. His life takes an unexpected turn when he falls in love with Midge McSorley, a fellow patient on a different unit. What follows is a tumultuous 14-year relationship characterized by ups and downs. Warren eventually finds his way out of the hospital, changes his first name, and begins a life with Midge. They secure jobs but face challenges in achieving independence, with Warren battling his demons of drinking, impulsiveness, and misfortune. Despite their ups and downs, their connection remains strong, even after they part ways. Warren's journey ultimately leads him to the western U.S., far from the life he once knew with Midge.