In Curse of the Iguana, Irene and Peggy venture out to seek a cure for whatever is making Irene "scientifically inaccurate." Along the way, they find pieces of information that seem to be leading Irene back to her old self. But can their quest for scientific accuracy go too far? At the end of the day, Peggy loves her girlfriend for who she is. If Irene is safe and happy, then everything is right in the world.