This is a practical guide to managing patients in an adult primary care setting with the emphasis on the word practical. This guide covers the majority of the underlying causes of the 30 most common presenting complaints in primary care, along with recommended management for common laboratory abnormalities. It also lists those potentially serious diagnoses that should not be missed. This guide also includes additional useful tips from a functional medicine perspective. The student or practitioner who learns and follows the information in this guide will be a solid primary care provider. This guide is a great resource for medical students to prepare for the family medicine shelf exam, and for the lay person who wants to have a more focused understanding of the common causes of common health issues. It is a more useful reference than the overwhelming information that comes from an internet search.